The Treatment of Advanced Malignant Melanoma

New therapeutical approaches for the treatment of malignant Melanoma

Malignant Mucosal Melanoma of the Maxillary Sinus

Sinus mucosal malignant melanoma, is a rare type of melanoma with poor prognosis which is usually occurred in the adults. This is a rare case of a 33-year-old man presenting 2-week-long headache and nasal obstruction with the emphasis on the importance of Immunohistochemical staining to help the diagnosis.

Malignant Melanoma: Staging and Treatment of Localized and Advanced Disease.

For most solid tumors, including melanoma, the most powerful predictor of recurrence and survival is the presence or absence of regional lymph node metastases. For patients with melanoma and stage III disease, the five-year survival decreases 40% compared to patients without nodal metastases. With the approval of interferon alfa-2b as the first effective adjuvant therapy for the high risk for r...

Malignant Melanoma of the External Auditory Canal:A Rare Entity

Introduction: Although malignant melanomas (MM) are common in the head and neck region; primary malignant melanoma of the external auditory canal (EAC) is rare.   Case Report: We present the case of a 50-year-old symptomatic man with a malignant melanoma of the external auditory canal, which clinically masqueraded as a haemangioma. The patient subsequently developed extensive loco-regional me...

Treatment of metastatic malignant melanoma.

The rapid increase in incidence of malignant melanoma has not been associated with better therapeutic options over the years. Single-agent chemotherapy or immunotherapy remain the treatments of choice when systemic therapy is offered. Dacarbazine (DTIC) is the chemotherapy of choice with a response rate of 16%. Other chemotherapies, including cisplatinum, paclitaxel, docetaxel and the DTIC anal...